SenCSs is a CSS framework that doesn’t provide a layout system but aims to take care of the rest, like:

fonts & font-sizes, paddings, margins, colors, tables & lists, headers, blockquotes and what more..

There are also styles for elements like errors, warnings or success messages which are parts of a standard web application.

SenCSs, although being fresh & currently in development, is a nice base to start with & improve depending on your needs.